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Medifast Trilivy Launch for Metabolic Health

Medifast Introduces Trilivy for Metabolic Health

Medifast, Inc. (NYSE: MED) has officially launched Trilivy, a new science-backed metabolic health system designed to help people achieve long-term wellness. The launch marks a major shift for the company as it moves beyond traditional weight loss solutions to focus on improving overall metabolic health.

The new platform also introduces Trilivy Reset Fueling, a redesigned meal replacement line powered by MetaVantage Technology™. The proprietary ingredient platform is designed to support metabolism by activating key metabolic pathways and promoting healthier lifestyle changes.

A New Chapter Beyond Weight Loss

The introduction of Trilivy replaces the OPTAVIA® brand and reflects Medifast’s broader vision for the future of health and wellness. The company says the transition addresses the growing challenge of metabolic dysfunction, a condition that affects more than 90% of adults in the United States.

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Official portrait of Nicholas Johnson, CEO of Medifast, highlighting the company's leadership in metabolic health and wellness innovation.

According to Medifast CEO Nick Johnson, Trilivy builds on the company’s long-standing foundation while creating a modern approach to metabolic health. He said the system combines scientific innovation, personalized coaching, and sustainable healthy habits to help individuals take greater control of their long-term

Metabolic Synchronization Powers the System

At the core of the Trilivy platform is Metabolic Synchronization®, a proprietary science designed to improve metabolic function through three key actions:

  • Burn: Targets harmful visceral fat stored around internal organs. Clinical research reported a 14% reduction in visceral fat within 16 weeks.

  • Preserve: Helps retain 98% of lean muscle mass, supporting strength, mobility, and energy during weight loss.

  • Protect: Supports healthy muscle to maintain an active metabolism and promote long-term weight management.

Together, these mechanisms aim to improve body composition while supporting sustainable metabolic health.

Three-Phase Metabolic Health Program

The Trilivy system follows a structured three-step approach that guides users through every stage of their wellness journey.

Phase 1: Reset

The first phase focuses on improving metabolic function and resetting the body’s metabolism.

Phase 2: Refine

Users work on enhancing metabolic flexibility while improving overall body composition.

Phase 3: Renew

The final phase supports long-term metabolic health, healthy aging, and sustainable lifestyle habits.

New Fueling Products Support Healthy Metabolism

Alongside the new system, Medifast introduced the Trilivy Reset Fueling product line. These meal replacements are enhanced with MetaVantage Technology™, which is designed to support normal fat metabolism, healthy insulin function, and a reduction in waist circumference.

The company plans to expand the Fuelings portfolio with additional formulations scheduled for release in August.

Coaching Remains a Core Part of Trilivy

Personal coaching continues to be one of Trilivy’s key strengths. Medifast’s nationwide network of independent coaches provides one-on-one guidance, accountability, and ongoing motivation throughout each participant’s health journey.

According to company-supported clinical research, participants using a coach-supported program lost up to 10 times more weight and 17 times more body fat than individuals attempting weight loss without coaching.

Building on More Than Four Decades of Experience

Backed by more than 45 years of clinical heritage, Medifast says Trilivy represents the next evolution of its mission to improve long-term health. By combining metabolic science, behavioral support, nutrition, and personal coaching, the company aims to help individuals reset their metabolism, build healthier habits, and achieve lasting wellness.

With the launch of Trilivy, Medifast positions itself as a leader in comprehensive metabolic health, offering an integrated system designed to support people far beyond traditional weight management.

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